Archana A
University of Madras, India
Title: A study to assess the noise stress-induced changes on cognition in Wistar albino rats
Biography
Biography: Archana A
Abstract
Background: In our modern lifestyle exposure to noise stress/pollution not only affects the auditory system but rather extend to the central nervous system.
Objective: The aim of the study is to investigate the effect of acute noise stress on cognitive functions in male Wistar albino rats.
Methods: Adult albino rats were randomly divided into two groups. Each group contains six animals. Rats exposed to acute noise stress (100 dB/4 hour) were compared with control animal and assessed for cognition by using T-maze, hole board test, open field test, marble burying test, and social interaction behavior.
Results: The rats exposed to acute noise stress shown the significance (p<0.05) of behavioral alterations such as impaired learning and memory, memory retention, increased fear and anxiety, obsessive-compulsive behavior, social avoidance and decreased social interaction.
Conclusion: The results report that acute noise stress affects the cognition and it became chronic may confer the increased risk of neurodegenerative disorders.