Jeffrey M. Chung received his Doctor in Medicine from Northwestern University Medical School. He is currently the Director of Epilepsy and Neurophysiology Programs at Cedars-Sinai Medical Center and an Associate Clinical Professor of Neurology at UCLA. He has presented at multiple national and international conferences on the localization of the epileptogenic zone with neuronal signal processing analysis and on the prediction of surgical decisions and outcomes with multi-modal probabilistic mapping techniques. His awards include Falks Medical Scholar, CARE Outstanding Patient Care Award, and the Clinical Research Fellowship Training Award from the Epilepsy Foundation, and multiple teaching awards.

Epilepsy,Neurophysiology and Neuronal signal processing analysis

Sharon Fernando is a US trained clinical psychologist with extensive experience in Primary Care facilities, multidisciplinary practice and most recently with the Industry’s only biopharma accelator. Dr. Fernando graduated with her Psy.D. from the Florida Institute of Technology with a specialization in pediatric clinical psychology. Fernando has more than six years of experience with Syneos Health and her current role is as a Senior Clinical Scientist within CST. She provides scientific oversight and clinical guidance for projects within CST and interacts with senior management, customers, and project teams to ensure scientific integrity and data quality in clinical trials. Dr. Fernando is also called upon to provide scientific input as needed to projects outside CST and contribute to business development activities with direct line management and mentoring responsibilities. Her therapeutic areas include CNS related studies.

CNS related studies, Epilepsy, Neurological Disorders

Long-Jun Wu completed his PhD in neurobiology from University of Science and Technology of China in 2004. He was trained as postdoctoral fellow at University of Toronto and Harvard Medical School (2004-2010). Dr. Wu was appointed as an Instructor at Harvard Medical School (2011-2012) and an Assistant Professor at Rutgers University (2012-2016). Since 2016, Dr. Wu is an Associate Professor in Department of Neurology at Mayo Clinic. His research interests mainly focus on neuroimmune interactions in normal and diseased brain. He has published more than 95 peer-review research papers, including those in Nature Neuroscience, Nature Communicaitons, Science Translational Medicine, Neuron, PNAS, Cell Reports etc.

Neuroimmune interactions in normal and diseased brain, Neuroscience and Neurobiology

Dagmar Amtmann is a psychologist and UW research associate professor with the Department of Rehabilitation Medicine. Dr. Amtmann's research interests include improving measures of patient reported outcomes such as pain, fatigue, and participation using modern measurement theories; statistical analytic approaches using multilevel and latent variable modeling; and instructional, information, and assistive technology for individuals with cognitive disabilities (with a particular focus on reading and writing technology for both children and adults).

Improving measures of patient reported outcomes such as pain, fatigue, and participation using modern measurement theories; statistical analytic approaches using multilevel and latent variable modeling; and instructional, information, and assistive technology for individuals with cognitive disabilities

Warren Boling trained in Neurosurgery at the University of Kentucky and then completed fellowships in Epilepsy and Stereotactic Surgery at Montreal Neurological Institute and Austin Repatriation Hospital, University of Melbourne. He joined the faculty at Montreal Neurological Institute where he was a member of the Comprehensive Epilepsy Program. He went on to develop the first comprehensive epilepsy program in West Virginia, at West Virginia University. Through his global outreach, Dr Boling developed the first surgery for epilepsy program in East Africa. He has been faculty at The University of Melbourne and University of Louisville. Currently Dr Boling is Chairman of the Department of Neurosurgery at Loma Linda University and Chief of Neurosurgery at Loma Linda University Hospital. Additionally, he directs the surgery of epilepsy program at Loma Linda University. Dr Boling has a particular interest in improving the lives of people with epilepsy and in elevating the medical and surgical treatment of neurological diseases in underserved regions of the world.

Epilepsy,Neurosurgery

• Dr Attarian is currently a professor of neurology and medical director of sleep medicine and sleep fellowship at Northwestern University. He graduated with a MD in 1992 from American University of Beirut and completed residency in Neurology at Upstate Medical University in Syracuse and fellowships in epilepsy and sleep medicine at University of Rochester and Hennepin County Medical Center respectively. He has Published 70 peer reviewed papers, 20 chapters and three textbooks. He has lectured nationally and internationally including Shanghai China and Moscow Russia and participated in 30 research projects and got three grants. He has won teaching awards.

Hrayr Attarian primary research interests are in sleep disorders in women and the treatment of parasomnias,Epilepsy.

Joseph I. Sirven, M.D., is a professor of neurology and editor-in-chief of Epilepsy.com. He is currently chair of the AAN Education Meeting Subcommittee and he is on the board of directors for the American Brain Foundation and the editorial board of Neurology Now. Previously, he served as director of education for Mayo Clinic's Arizona campus with oversight over all educational activities at the Arizona campus, including medical student rotations, residencies, fellowships, Ph.D. candidates, nursing, allied health and continuing medical education programs. He was the previous chair of Neurology at Mayo Clinic's campus is Arizona and the previous vice chair of the Epilepsy Section of the American Academy of Neurology, chair of the Communication Council for the American Epilepsy Society and former chair of the Professional Advisory Board for the Epilepsy Foundation.

Epilepsy and seizure treatments in adults and children (particularly older adults) Epilepsy surgery Electroencephalography Investigational anti-epilepsy drugs Status epilepticus Vagal nerve stimulator Ketogenic diet

Dr. Alain L. Fymat is a medical-physical scientist and an educator who was educated at the Universities of Bordeaux and Paris-Sorbonne, France, and the University of California at Los Angeles. He is the current President/CEO and Professor at the International Institute of Medicine & Science. He was formerly Professor of Radiology, Radiological Sciences, Radiation Medicine (Oncology), Critical Care Medicine, and Physics at several U.S. and European Universities. His current research interests lie at the interface between science and medicine (neurological disorders; precision medicine; nanobiotechnology; nanomedicine; genetics/epigenetics/ecogenetics; and drug delivery across the brain protective barriers). He has extensively published (~350 scholarly publications) and lectured in several national and international academic, professional, governmental and industrial venues. He is a a Board member of several institutions, and Editor-in-Chief, Honorable Editor or Editor of twelve scientific Journals.

Radiology, Medicine

Antonio Gambardella is full professor of Neurology in the Department of Medical and Surgical Sciences, University Magna Graecia - Catanzaro, Italy. He is a clinical neurologist and clinical researcher with a special interest in establishing close research links with basic scientists. His group, together with molecular genetic collaborators in Italy, discovered in 2000 the beta2 nicotinic acetylcholine receptor gene for nocturnal frontal lobe epilepsy and subsequently has been involved in the discovery of other epilepsy genes. A more recent important scientific result has been the discovery of novel gene KCNT1 associated with a severe form of progressive myoclonus epilepsy. He has also focused on clinical and neurophysiological aspects, and genetics of temporal lobe epilepsy, the most common type of focal epilepsy. He is currently an active investigator of the "Epi25" Collaborative group that has developed from an initiative coming out of the NIH National Human Genome Research Institute (NHGRI) and the International League Against Epilepsy (ILAE) Consortium on Genetics of Complex Epilepsies to make more rapid progress towards fully understanding the inherited components of epilepsies

Epilepsy, Neurology

Natalia Rodríguez Álvarez is the Postdoctoral research Scientist in the department of Physiology and Medical Physics in the Epilepsy Research Group at the Royal College of Surgeons in Ireland. Combining the principles of molecular biology and neurobiology, electroencephalography, pharmacology and genetics at both undergraduate and postgraduate level has led to a broad knowledge base in a multidisciplinary field with additional experience in drug discovery and biomarkers.

Epilepsy,Medicine

Dr. K. S. Ravi holds M.D. Anatomy degree from India’s most prestigious Institute, JIPMER Pondicherry.He has worked as an Assistant Professor in Sri Venkateshwara Medical College Hospital & Research Centre in Pondicherry & Sri Muthukumaran Medical College Hospital & Research Institute, Chennai. Before Joining AIIMS Rishikesh on 18th August 2012 as faculty of Anatomy, Dr. Ravi was working as Assistant Professor and Course Director & Head of Anatomy at School of Medicine, Spartan Health Sciences University, St. Lucia, North America. Dr.Ravi has been Assistant Dean(Academics) and presently working as Sub-Dean(Academics),AIIMS Rishikesh.Apart from his contributions to the field of medicine, Dr. Ravi is also a creative writer. He was awarded the “Best Creative Writer” in 1997 for one of his stories. His articles have been published in various magazines and leading national newspapers of India, including- The Times of India, The Pioneer and The Hindustan times. He has furthered his literary interests by serving on the editorial boards and reviewers of several National – International Journals and magazines

Neuroanatomy,Medicine,Health Sciences

Dr.Ameen Al-KAMALI is professor of Neurosurgery at Ain Shams University. Faculty of medicine at Sana'a University

Neurology, Neurosurgery,Child and Adolescent Neurology

Roberto Alexandre Dezena M.D. is from Federal University of Triângulo Mineiro, Uberaba, Brazil (2003), medical residency in Neurosurgery at Santa Casa de Misericórdia de Ribeirão Preto, Brazil (2009), Ph.D. in Neurosurgery at Ribeirão Preto Medical School of University of São Paulo, Brazil (2011), and Postdoctoral Fellowship at Federal University of Triângulo Mineiro, Uberaba, Brazil (2014). Fellow of Eberhard-Karls Universität Tübingen, Germany, Hiroshima University, Japan, and Saint Louis University, USA. In Brazil, he is Full Member of Brazilian Society of Neurosurgery (SBN) and Brazilian Academy of Neurosurgery (ABNc), besides vice president of Minas Gerais Neurosurgery Society and member of deliberative counsil of Brazilian Academy of Neurosurgery. Internationally, he is Fellow of World Federation of Neurosurgical Societes (WFNS), Active Member of International Federation of Neuroendoscopy (IFNE), Active Member of International Society for Pediatric Neurosurgery (ISPN), Active Member of Walter E. Dandy Neurosurgical Society (WEDNS), and Full Member of both Latin American Federation of Neurosurgery Societes (FLANC) and Latin American Group of Studies in Neuroendoscopy (GLEN). Currently is Associate Professor and Chief of Division of Neurosurgery, Clinics Hospital, Director of Neurosurgery Residency Program and Professor of Postgraduate Program in Health Sciences and Postgraduate Program in Applied Biosciences, all at Federal University of Triângulo Mineiro, Uberaba, Brazil. Director of the Reference Center for Continuing Education of Latin American Federation of Neurosurgery Societes (FLANC), at the same university. Neurosurgical activities in Microneurosurgery (vascular and neuro-oncology), Endoscopic Neurosurgery, Pediatric Neurosurgery, Spine Surgery and Neurotrauma. Furthermore is editorial board member and reviewer of several international scientific journals, highlighting World Neurosurgery (WFNS), Neurological Research (Maney) and Journal of Neurosurgical Sciences (Minerva).

Neurology,Neurosurgery , Pediatric Neurosurgery, Endoscopic Neurosurgery,Neurotrauma, Spine Surgery

Riaz Ahmed Competent and well trained neurologist with 2 European certifications and Fellowship: Fellow of Royal College of Paediatrics and Child Health, UK as well Fellow of Royal College of Physicians of Ireland - Comfortable with all aspects of neurology, including Epilepsy management In Paediatrics and neurophysiology (electroencephalography and electromyography). Has more than 40 publications in Peer viewed Neurology Journals - Editorial board member in 3 International Neurology Journals. - Member of International Child Neurology Association, Asian Oceanean Child Neurology Association, Indian Neurological Society, Infantile |Seizure Society & American Academy of Neurology.He is currently working as Consultant & Head of Paediatric Neurology at KFAFH

Epilepsy management In Paediatrics and neurophysiology (electroencephalography and electromyography).

Dr. Dan Suiaga With a rich experience in all types of neurosurgical interventions, Dr. Dan Suiaga is recognized for interventions in complex spinal surgery (implants and spinal reconstruction, etc.), but also for cerebral vascular surgery or skull base. Although he started his professional training at the neurosurgery department of the University Hospital in Cluj-Napoca, Dr. Dan Suiaga continued to train outside the borders of Romania, in countries such as Switzerland, Israel, Germany and South Africa.

Clinical Science

Dr. Francisco Javier Ruiz Miyares is a Neurologist with a varied range of interests within clinical neurology, mainly epilepsy of childhood onset. Diverse aspects from teaching to research within a clinical praxis framework, encompass his goals including semiology-semiothecnia, neurophysiology, epidemiology with an exchange platform as a congress organizer, being the former Neurology Conferences, now NeuroSantiago events, a successful pathway of interaction amongst many neuroscientists from diverse part of the world. Master of Sciences in Infectology, Assistant Professor and Second Degree Specialist and Researcher, was CME coordinator of the World Federation of Neurology in the eastern part of the island more than 10 years

Neurology,Epilepsy,Neuroscience,Pediatric Neurology,Neurophysiology and Epidemiology

Intractable seizures plague approximately a third of epilepsy patients. Despite their prevalence, the mechanisms underlying intractable seizures remain unclear and difficult to study. One factor clouding our understanding of seizure intractability stems from existing animal models of epilepsy, which have not specifically modeled intractable seizures or genetic disorders that often associate with intractable seizures, like Focal Cortical Dysplasia (FCD) or Tuberous Sclerosis Complex (TSC). New animal models are greatly needed to understand the underlying causes of intractable seizures and develop new therapies aimed at these indications. Using in utero electroporation to transfect a small population of neurons in vivo with constitutively active mutant of Ras homolog enriched in brain (RhebCA), we have successfully developed a new mouse model of spontaneous epilepsy based on the genetic etiology of mTOR-o-pathies. This model recapitulates both anatomical and behavioral phenotypes of human TSC and FCD. RhebCA transfected animals develop focal cortical malformations that contain dysplastic neurons, cortical dyslamination and white matter heterotopia. Seizures also spontaneously develop as early as postnatal day18, and persist throughout entire lifespan of the animals (2 years). Seizures are the only complication these animals have, otherwise they are completely healthy, making them ideal subjects to study mechanistic causes of seizures and seizure-dependent downstream behavioral and physiological effects. With this model, we have elucidated several mechanisms that contribute to seizure-genesis in TSC and FCD. Lastly, we also use this model to develop new therapies, including novel cannabinoids and RNA interference approaches to mitigate refractory seizures

Neuroscience , Neurosurgery

Dr.Omar García is currently a Professor from university Anáhuac with the Department of Neurology.He is the Neurosurgeon at Mexican Society of Neurological Surgery. Dr.Omar done his education from National Autonomous University of Mexico. He is also invited Professor at Pre and postgraduate courses. He is the member of Neuro trauma section

Neurosurgery,Tumors, Skull base, Derivation systems,Vascular surgery,CNS infections Spine surgery,Congenital disease,Degenerative disease,Tumors Fixation and instrumentation Trauma

Annamaria Vezzani obtained her PhD degree in Neuropharmacology in Milano at the Mario Negri Institure for Pharmacological Research. She spent her post-doctoral period at the Univeristy of Maryland in Baltimore working on the mechanisms of seizures generation in experimental models of epilepsy. Additional post-doctoral periods were done at the Univeristy of Stockholm and at the Karolinska Institute. She was on sabbatical at the Albert Einstein College of Medicine in 2002 in the laboratory of Developmental Epilepsy. She studies the biochemical and molecular mechanisms involved in the pathogenesis of seizures and epileptogenesis using experimental models. The present research is focused on the role of neuroactive inflammatory mediators in aberrant neuronal excitability underlying seizures. Focus of research is also on the mechanisms of pharmacoresistance. She has published over 160 original papers, several book chapters and reviewes in peer-reviewed high impact scientific journals (h-index 62). Since 1997 she is Head of the Laboratory of Experimental Neurology in the Department of Neuroscience at the Mario Negri Institute for Pharmacological Research, Milan, Italy. She is member of the Editorial Board variuos scientific journals includingf Epilepsy Res, Epilepsy and Treatments and Neuroscience, and she has been for 8 years Associate Editor of Basic Science for Epilepsia. She has been appointed of the Chair of the Commission on Neurobiology of International League Against Epilepsy (2005-2009) which is promoting initiatives for improving translational research in epilepsy. She is now liason member of the Commission on Neurobiology and active member of the CEA of the ILAE and various AES committees. She received the Research Recognition Award for translational research in 2009 by the American Epilepsy Society.

Neuropharmacology,Experimental Neurology,Translational Research in Epilepsy

Dr. Sanjoy Sanyal is Associate Dean, Clinical Neuroscience Professor, Surgeon and Informatician in Texila American University, Guyana, South America. He holds double Master's degrees from India and UK. He has published more than 50 papers in print and online journals. He is a Neuroscience editor and peer-reviewer of WebmedCentral. He has posted more than 300 Neuroscience videos online, accompanied by his running commentaries. He is currently writing a Neuroscience book for medical students. He has presented papers in more than 10 international forums. He holds a provisional patent from USPTO on a computerized program for staging 26 human cancers.

Neuroscience

Dr.Jera KRUJA is a Member of Scientific Committee at European Academy of Neurology and Professor of Neurology at Mother Theresa University Hospital Center. Since 2014 she is (European representative) at Teaching Course Committee, World Federation of Neurology. During 2013-2014 she is a Rector of University of Medicine, Tirana and Member of editing board of OA Publishing London, WebMed Central Brain Editor, Albanian Medical Journal, Bulletin of Medical Sciences, University of Medicine, Tirana. She worked at Health National Contact Point, European Commission, CORDIS Fp7 programme(2010-2013). From 2003, she is a reviewer of European Journal of Neurology, Clinical Epidemiology, Neuropsychiatric Disease and Treatment, Journal of Epidemiology and Community Health, Journal of Pediatric Epilepsy. She is a Trainer of European Academy of Epilepsy since February 2003. She is the President of Albanian Society of Neurology (ASN) during 1998-2007.

Neurology, Neuroradiology, Epidemiology

Dr. Alberto E. Musto, M.D., Ph.D., F.A.E.S., is an Assistant Professor of Pathology and Anatomy, one of the Module Directors of the CareForward Curriculum, School of Medicine and Director of the Neuroanatomy, School of Health Professionals at Eastern Virginia Medical School in Norfolk, Virginia. Dr. Musto integrates an interdisciplinary approach in medical education and mentorship activities in neuroscience research in order to enhance research and diversity in the new medical curricula. Dr. Musto’s scientific goal is to identify potential biomarkers and preventive therapies for epilepsy. He has been bestowed with a lifetime professional honor in recognition of his accomplishments and dedication to excellence in epilepsy by the American Epilepsy Society. He has published in major journals in the field of neuroscience and epilepsy and he has been a member of NIH grant review study sections. Prior to join EVMS, Dr. Musto was at Louisiana State University Health Science Center, New Orleans, where he completed his postdoctoral fellowship in neuroprotection and worked as an Assistant Professor of research in Neuroscience and Neurosurgery. Prior to that, Dr. Musto started his career in Buenos Aires, Argentina where he received board certifications in both neurology and radiology, completed postgraduate studies in medical education, management in health systems and a doctoral thesis in neurobiology. Dr. Musto has been involved in academic medicine during his entire career and is a regular speaker at national and international conferences.

Neurobiology and Neuroanatomy

Dr. Hallowell served more than eight years as Associate Dean for Research and Sponsored Programs in Ohio University’s College of Health and Human Services and six years as Director of the School of Hearing, Speech and Language Sciences. Given her extensive experience in boosting successful publication and extramural funding successes of students and faculty members, she is frequently invited to provide action-focused workshops on research career development and on ways to foster productive interdisciplinary and international collaboration in research and education.

Neurogenic Language Disorders, Global Health, Technology Transfer, Engaged Teeaching/Learning Methods

Jane Paulsen is a Chair in Neuroscience from Roy J. Carver, and Professor of Psychiatry, Neurology, Psychology. Her education is BS, Psychology with honours, Simpson College, Indianola, and completed IAMS, Psychology, from Columbia University, New York, NY. She did PhD in Counselling Psychology (APA accredited) from University of Iowa. She got Post Doctorate in Neuropsychology specialization in Alzheimer's disease from University of California, San Diego, and CA. Her Research Summary includes neural basis of cognition; preclinical deficits in dementia gene-carriers; frontal subcortical deficits, particularly Huntington's disease Research in this laboratory uses tools of neuropsychology and cognitive psychology to examine behavioral correlates of brain dysfunction. Topics of current interest include subtypes of Alzheimer's disease, preclinical cognitive deficits associated with gene-carriers of Huntington's disease and clinical/imaging correlates of cognitive measures. Functional MR and PET are used to examine frontal-striatal circuitry dysfunction in these disorders.

Alzheimer's disease, Huntington's disease , Parkinson's disease, Epilepsy.

Mr Mbusomuni Mahlalela (the national director) is the founder and of the Swaziland Epilepsy Organization. The organization was founded in 2002 and registered in 2004. The mandate for the organization is to raise awareness and to help reduce stigmatization associated with people living with epilepsy in the country. In 2006 the SEO affiliated with the IBE. The national director was a vise chairperson in the Road Safety Awareness Council(Epilepsy and Driving). Meetings that have been attended by the national director includes inter alia; Epilepsy Congress in Rome, Dubai 2 times ,Kenya and South Africa.The SEO has worked closely in sharing ideas with the South African Epilepsy Organization which has ensured the introduction of the South African Epilepsy golf in Mpumalanga branch. In Swaziland the national director has ensured the initial start up of the following; 1.epilepsy and driving campaign 2. Swaziland golf day (annual event) 3.Epilepsy yellow valentines 4.Epilepsy marathon 5.Epilepsy happy mother's day 6.Epilepsy cycling 7.Epilepsy support groups initiatives to help sustain the livelihoods for people living with epilepsy. 8. Mbusomuni Mahlalela has worked closely with the Swaziland government and parliament to ensure the availability of epilepsy equipment, and drugs furthermore the rights of people living with epilepsy . and the our website can let what I did for the country about epilepsy.

epilepsy

Educational Background and Academic Titles 1968 M.D., Tokyo University Faculty of Medicine 1968 Residency at Tokyo University Hospital 1969 Residency at Tokyo Police Hospital 1973 Research Fellow at Sainte Anne Hospital(Professeur J Talairach), 1973-1975 1976 D.M.Sc.,Board of Japan Neurological Surgery 1981 Associate Professor, Department of Neurosurgery, Tottori University 1984 Professor, Department of Neurosurgery, Tottori University 1995 Director, Institute of Neurological Sciences, Tottori University 1998 Chairman and Professor, Department of Neurosurgery, Neurological Institute, Tokyo Women’s Medical University 2009 Emeritus Professor of Tokyo Women’s Medical University Honoured President of Moriyama Memorial Hospital(Tokyo) 2012 Honoured President of Moriyama Memorial Hospital(Tokyo) Honoured President of Shin Yurigaoka Genreral Hospital(Kanagawa) 2016 President of Tokyo Neurological Center Hospital Board ECFMG 1968 Japanese Neurosurgical Society (No 699) Japanese Epilepsy Society (No 33) Japanese Rehabilitation Society (Clinical Board 3718) Japanese Cerebral Stroke Society (No20030046) Japanese Neuroendoscope society (No1) Endoscopy for pituitary adenomas, craniopharyngiomas, and acoustic tumors. Japanese Headache Society, Japanese Dementia Society

Neurosurgery , Epilepsy

My background consists of hippocampal anatomy at light and electron-microscopic levels, in non-human primates and rodents. During PhD my work was focused on experimental models of temporal lobe in rodents. During this time I gained experience in anatomical studies, specially aiming to identify seizure-induced damage in the entire brain and in hippocampal plastic changes caused or related to seizures. My first postdoctoral experience was in the anatomy department under supervision of Ole Peter Ottersen, when I gained abilities to use the electron microscopy as tool to identify the sublocalization of glutamate receptors in the hippocampus. Back to Brazil, now under supervision of Luiz Mello, we focused on the establishment of a new model of temporal lobe epilepsy in non-human primates. I conducted studies examining behavioral and electrophysiological recordings of seizures as well as histological analysis. At the same time I started to use the magnetic resonance imaging as tool to investigate morphological changes in several brain areas after status epilepticus and in chronic epilepsy. In 2006 I got a permanent position as professor at Universidade Federal of Sao Paulo. Since them, I have followed two research lines: (1) experimental models of temporal lobe epilepsy and (2) experimental models of neonatal pain. In both lines I have focused my research on neuroplastic changes caused by these models and its consequences on electrophysiological and behavioral levels. By using Manganese-enhanced MRI, we have been able to demonstrate that hippocampal remodeling after seizures can be followed in both research models. From my research on epilepsy, I was able to demonstrate that thalamic Deep Brain Stimulation (DBS) is a valuable tool to reduce cell apoptosis and inflammatory responses after pilocarpine-induced status epilepticus. By conducting DBS experiments in the chronic phase of pilocarpine, my students and I were able to demonstrate that it causes reduction of spontaneous seizures, reduces the hippocampal excitability and increases adenosine in the same area. The mechanisms underlying the adenosine actions in response to thalamus DBS are still under investigation. I am presently engaged in a number of collaborative efforts between my laboratory and various other laboratories focusing to understand how DBS affects neural networks. These studies include behavioral evaluation, record EEG and ex-vivo electrophysiology and MRI. These collaborations allow me to draw from a broad array of scientific expertise. In summary, my combined research experience in surgical implantation of electrodes, DBS, behavioral neuroscience and MRI will afford me an essential expertise and experience that will facilitate the successful implementation of the experiments outlined in this application.

Epilepsy

Leon D. Iasemidis was born in Athens, Greece, and received the Diploma degree in Electrical and Electronics Engineering from the National Technical University of Athens, Athens, Greece. He subsequently earned the M.S. degree in Biomedical Engineering, the M.S. degree in Physics and the Ph.D. degree in Biomedical Engineering from the University of Michigan, Ann Arbor, MI, USA. He was a Postdoctoral Fellow at the University of Michigan (1991–1993), a Research Assistant Professor of electrical and computer engineering, neurology, and neuroscience at the University of Florida, Gainesville, FL, USA, the Director of the clinical neurophysiology laboratory, neurology service, Malcolm Randall Veterans Affairs Medical Center, Gainesville, FL (1993–1997), and a tenured Associate Professor in biomedical engineering at the Arizona State University, Tempe, AZ, USA. Since 2012, he has been the Rhodes Eminent Scholar Chair and Professor of biomedical engineering at the Louisiana Tech University, Ruston, LA, USA, the Founder and Director of the Brain Dynamics Laboratory (http://www.braindynamics.latech.edu), the Director of the multidisciplinary Center for Biomedical Engineering and Rehabilitation Science (http://coes.latech.edu/cbers) at Louisiana Tech University, and a Professor Emeritus of the Arizona State University. He held an adjunct professorship in neurology (2009–2012) at Mayo Clinic Arizona, and currently holds adjunct professorships in neurology (2013) at the Louisiana State University Health Sciences Center, Shreveport, LA, and neurosurgery (2015) at the University of Arkansas for Medical Sciences (UAMS), Little Rock, AR, USA. His research interests include the areas of biomedical signal processing, complex systems theory and nonlinear dynamics, neurophysiology, monitoring and analysis of the electrical and magnetic activity of the brain in epilepsy and other brain dynamical disorders, intervention and control of CNS. His research has been highlighted in multiple forums, including the New York Times, Discover magazine, the Teaching Company, and the American Society for the Advancement of Science. He is internationally recognized as an expert in nonlinear dynamics, the detection, prediction and control of crises in complex coupled systems, is one of the founders of the field of seizure prediction and of two companies in this area. His research and more than 100 peer-reviewed publications, patents, interdisciplinary conference organizations, presentations, and invited talks have stimulated an international interest in the prediction and control of epileptic seizures and understanding of the mechanisms of epileptogenesis. His research has been funded by National Institute of Health, VA, Defense Advanced Research Projects Agency, National Science Foundation, DoD, the Whitaker Foundation, the Epilepsy Foundation of America, CURE, the Science Foundation of Arizona, and medical device industry. Prof. Iasemidis is a Fellow of the American Institute of Medical and Biological Engineers (AIMBE) and a Fellow of the National Academy of Inventors (NAI). He has served on the editorial board of Epilepsia, the IEEE Transactions on Biomedical Engineering and the International Journal of Neural Systems, and currently is an Associate Editor of the Annals of Biomedical Engineering and a member of the editorial board of the journal of Epilepsy Research. He is a reviewer for the National Institutes of Health, the National Science Foundation, and several other national and international funding agencies and foundations.

Brain Dynamics in Epilepsy

Domenico Ursino received the MSc Degree in Computer Engineering from the University of Calabria in July 1995. He received the PhD in System Engineering and Computer Science from the University of Calabria in January 2000. From November 2000 to December 2004, he was an Assistant Professor at the University Mediterranea of Reggio Calabria. From January 2005, he is an Associate Professor at the University Mediterranea of Reggio Calabria. From November 2015, he is a Vice Rector, Responsible for Information Technology, of his University. He is author of more than 160 papers. His research interests include Neurological Network Analysis, Social Internetworking, Social Network Analysis, Knowledge Extraction and Representation, Source and Data Integration, Multi-Agent Systems, Recommender Systems.

Neurological Network Analysis, Social Internetworking, Social Network Analysis, Knowledge Extraction and Representation, Source and Data Integration, Multi-Agent Systems, Recommender Systems.

Dr. Patricio Espinosa is a neurologist in Boca Raton, Florida and is affiliated with Boca Raton Regional Hospital. He received his medical degree from Universidad Central del Ecuador School of Medicine and has been in practice between 11-20 years. Dr. Espinosa accepts several types of health insurance, listed below. He is one of 23 doctors at Boca Raton Regional Hospital who specialize in Neurology.

Epilepsy, Neurology, Sleep Disorders, Telemedicine, International Health, Public Health, Clinical Trials, Neuroepidemiology

Dr. Julio Sanchez Albisua is the President of Spanish Brain Council and Professor of Department of Surgery in Universidad Autonóma de Madrid. And also he is the Head of Department of Neurosurgery in Jimenez Diaz Foundation Hospital.

Neurosurgery,Epilepsy, Stroke and other Cerebrovascular diseases

Dr. Rodriguez is assistant professor of Neurology at New York University School of Medicine and Co-Director of the New York Sleep Institute. He graduated with honors from the University of Panama Medical School. After his Internal Medicine training at St. Vincent's Hospital in New York he completed a neurology residency at Tufts-New England Medical Center, in Boston, MA. Subsequently, he completed two years of subspecialty fellowship in EEG/Epilepsy and Sleep Disorders Medicine at Mayo Clinic, Rochester, MN. Dr. Rodriguez is Board certified in Neurology, Internal Medicine, Sleep Medicine and clinical Neurophysiology.

Epilepsy, Neurology, Sleep Medicine

Dr. Topçu graduated from Hacettepe Faculty of Medicine in 1977. She started her specialty education on pediatrics in Hacettepe Children’s Hospital and became a specialist of pediatrics in 1981. She worked in Hacettepe Pediatric Pathology Unit as a fellow between 1981 and 1984. She started her subspecialty on Child Neurology in 1985. She became a specialist of Child Neurology in 1988. In the same year, she became an associate professor of Pediatrics. In 1988, she received education on pediatric neurology, EEG, and evoked potentials in Great Ormond Street Hospital for Sick Children in London and Southampton Wessex Neurology Center Clinical Neurophysiology department. Between the years of 1991 and 1994, she completed the doctorate program of Neurological Sciences Institute clinical electrophysiology and gained a doctoral competency. She became a professor of pediatrics in 1995. She is the founding member of the Turkish Association for Child Neurology, the Turkish Foundation for Child Neurology and the Association for Protecting the Families with Rett Syndrome.

Neurometabolic and neurodegenerative diseases, epilepsy, autistic spectrum diseases, and neurogenetics

Dr.Federico Zara is the Head of Laboratory of Neurogenetics. Working in the field since 1994. Research interests are Genetics and Pharmacogenomics of Epilepsies (Severe Myolonic epilepsy of Infancy autosomal dominat cortical tremor and epilepsy, Idiopathic generalized epilepsies, febrile seizures) - Genetics of Muscular and Neurodegenerative disease (Dystrophinopathies, Limb-girdle muscular dystrophies, Muscular glyocogenosis, Leukoencephalo- pathies). Epileptogenesis (electrophysiology of ion-channels, in collaboration with other groups)

Epilepsy, Genetics and Pharmacogenomics and Epileptogenesis

Dr.Jera KRUJA is a Member of Scientific Committee at European Academy of Neurology and Professor of Neurology at Mother Theresa University Hospital Center. Since 2014 she is (European representative) at Teaching Course Committee, World Federation of Neurology. During 2013-2014 she is a Rector of University of Medicine, Tirana and Member of editing board of OA Publishing London, WebMed Central Brain Editor, Albanian Medical Journal, Bulletin of Medical Sciences, University of Medicine, Tirana. She worked at Health National Contact Point, European Commission, CORDIS Fp7 programme(2010-2013). From 2003, she is a reviewer of European Journal of Neurology, Clinical Epidemiology, Neuropsychiatric Disease and Treatment, Journal of Epidemiology and Community Health, Journal of Pediatric Epilepsy. She is a Trainer of European Academy of Epilepsy since February 2003. She is the President of Albanian Society of Neurology (ASN) during 1998-2007.

Neurology, Neuroradiology, Epidemiology

Dr. Konstantin Slavin is a neurosurgeon in Chicago, Illinois. He is affiliated with multiple hospitals in the area, including Advocate Christ Medical Center and Alexian Brothers Medical Center. He received his medical degree from Azerbaijan State Medical Institute and has been in practice for 26 years. Dr. Slavin accepts several types of health insurance, listed below. He is one of 5 doctors at Advocate Christ Medical Center and one of 12 at Alexian Brothers Medical Center who specialize in Neurological Surgery.

Deep brain stimulation therapy,Parkinson’s Disease,Dystonia and other movement disorders

Professor Durodami Radcliffe Lisk is presently appoint as Consultant Neurologist in Ministry of Health, Coordinator of Epilepsy Project in Sierra Leone & Honorary Consultant Neurologist Basildon University Hospital in Essex UK. He has been awarded in many field of Neurology especially in Epilepsy including Gold Award for service development awarded by the South West Essex Primary Care Trust (National Health Service, UK) for the development of an Epilepsy service. He published number of books and author of many articles published in many reputed Journal. He is also an active Editorial Board member & Reviewer for many Journal.

Epilepsy pattern and prevalence in Sierra Leone Effects of lowering blood pressure in patients with recent strokes. Stroke risk factors in Sierra Leonean Africans. Pattern of neurological diseases in African populations. Medication compliance particularly in epilepsy Morphometric and biochemical changes in diabetic neuropathy in mice Biochemical changes in the liver of rats on low protein diet.

Dr. Peter Kaplan is Professor of Neurology and serves as the Director of Epilepsy and EEG at Johns Hopkins Bayview Medical Center. He focuses on epilepsy, clinical neurophysiology and nonconvulsive status epilepticus. He has written extensively about these subjects as well as about eclampsia and neurologic disease in women. Dr. Peter Kaplan received his medical training from St. Bartholomews Medical School, University of London. He then obtained membership to the Royal College of Physicians in England. He completed his residency in neurology at Duke University Medical Center. He completed fellowships in epilepsy and clinical neurophysiology at the same institution.

Clinical Neurophysiology, Epilepsy, Epilepsy and Pregnancy, Neurology.

He is a Professor in Department of Neurobiology

Neural Injury and Repair

Brent T Harris is a Director of Neuropathology and Associate Professor of Neurology & Pathology in Georgetown University Medical Center, USA. As a neuropathologist and physician-scientist he has clinical, research and teaching interests in neurological diseases. He has active collaborations and research programs in his own lab in the areas of neurodegeneration and CNS neoplasia. His primary interest is in understanding how mechanisms of inflammation and glial-neuronal communication influence the pathophysiology of neurological diseases. In addition to investigating disease processes he also seeks to uncover targets for pharmacological intervention.

CNS neoplasia, Neuropathology, Brain Neoplasms, Neurodegenerative Diseases and Neuroglia

Dr. Milivoj Veličković Perat is a Director at Academy of Developmental medicine in Slovenia. He was born on June 3, 1937. Specialised in neuro-psychiatry and developmental neurology. Since 1973 he was a member of staff at the University Medical Centre, Paediatric Hospital in Ljubljana. He was a Professor at Medical Faculty of University of Ljubljana and a Head of the Centre of Developmental Neurology, National Register of at Risk Newborns, and the Cerebral Palsy Centre. For more than 40 years he has been working on the development of the central nervous system and the early brain damage, especially in the field of cerebral palsy.His post-graduate work was completed with Prof. Heinz Prechtl at the Institute of Developmental Neurology at Groningen University in the Netherlands. After research into possible risk factors in cerebral palsy he received his scientific doctorate (PhD) in 1983. He has organised several international and national professional conferences, symposia, congresses, workshops, and courses in the field of child and developmental neurology. In his professional field he has published more than 100 books and articles on medicine, particularly on child and developmental neurology.

Neuro-psychiatry,Developmental neurology, Development of the central nervous system and the early brain damage,especially in the field of cerebral palsy. Early detection of brain damage and developmental abnormalities.

Dr. Akman is Associate Professor of Clinical Neurology and Pediatrics of the Division of Pediatric Neurology, Departments of Neurology and Pediatrics, College of Physicians & Surgeons of Columbia University. Dr. Akman was born and educated in Ankara, Turkey where she graduated with Honors from the School of Medicine, Ankara University. Dr. Akman completed her training in Child Neurology at State University of New York; Clinical neurophysiology & Epilepsy at Boston Children's Hospital, Harvard Medical School. Subsequently, Dr Akman joined the Division of Pediatric Neurology and Pediatric Epilepsy at Columbia Presbyterian Medical Center and participated in clinical education and patients' care until 2008. Between 2008 and 2010, Dr Akman worked as the Director of Clinical Epilepsy Research at Texas Children's Hospital, Baylor College of Medicine. Dr Akman recently re-joined the Division of Pediatric Neurology and Epilepsy as the Director of Pediatric Epilepsy.

Cognitive and behavioral problems associated with epilepsy, imaging modalities used for epilepsy diagnosis and epilepsy surgery

Noormamode Youssouf, is the founder-President of Edycs Epilepsy Group in the Republic of Mauritius including Rodrigues island. Under his present leadership, he establishes the Edycs Epilepsy Health Service Centers in both Mauritius and Rodrigues islands with the support and collaboration of the Government and the Private Sector thro the CSR funding programme. . Noormamode Youssouf, graduated in Project Management, has also served on different committees mainly as Vice President of the Mental Health Federation, Vice Honorary President of the Macoss, umbrella organisation for Ngos in Mauritius, the National Youth Council, the Ngo Trust Fund, the Ministry of Social Security Visitors Rehabilitation Centers and currently he is occupying the position of Chair at the International Bureau for Epilepsy Africa Regional Committee.

Epilepsy