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Jinwei Zhang


Jinwei Zhang

University of Exeter, UK

Biography

Jinwei Zhang has a long track record of ground-breaking discovery in the field of cellular chloride homeostasis and cell volume regulation. He has published over 45 articles in peer-reviewed journals (with 20 first-author or corresponding author, total citations of 1600, h-index  20), including several in the highest impact journals, including Nature Medicine, Cell Metabolism, Neuron, and Nature Communications. Dr Zhang then made fundamental discoveries regarding the role of WNK-SPAK/OSR1-NKCC1/KCCs signalling pathway in Cl- homeostasis through KCC2Thr906/1007 and NKCC1 Thr203/207/212 phosphorylation.

Abstract

Abstract : Activation of K+–Cl-–cotransporter KCC2 by inhibiting the WNK-SPAK kinase signalling as a novel therapeutic strategy for Epilepsy