Epilepsy Surgery: Indications and Outcomes

Epilepsy surgery is a critical option for individuals with drug-resistant epilepsy, providing a potential cure for those whose seizures cannot be controlled with medication alone. The surgical approach involves removing or altering the brain tissue responsible for seizure generation. Key indications for epilepsy surgery include the presence of a well-defined epileptogenic focus that can be safely resected and the failure of multiple AEDs to achieve seizure control. Pre-surgical evaluation typically involves a combination of neuroimaging techniques, such as MRI and PET scans, and invasive monitoring, including intracranial EEG, to precisely localize the seizure focus. Surgical options range from resective surgery, such as temporal lobectomy, to less invasive procedures like laser ablation. Outcomes of epilepsy surgery can be highly favorable, with many patients achieving significant seizure reduction or complete freedom from seizures. However, the decision to proceed with surgery involves careful consideration of potential risks, including cognitive and neurological deficits. Post-surgical care includes ongoing monitoring and rehabilitation to address any functional changes and to ensure optimal long-term outcomes

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